Yes, better control of glucose metabolism is well know to improve lifespan and health. But this effect will depend to an unknown extent on genotype/genetic background and of course, diet, age, and sex.
Ditto for rapamycin. The mouse studies on rapamycin and longevity increases are impressive bit this is now old news. Rapamycin is effect in both sexes of mice and can extend life expectancies even after the mouse equivalent if middle age (20 months and up).
It would be good to know if and how this positive rapamycin effect interacts with exposure to pathogens as a function if sex and age and genotype.
Recent data from Kaeberlein TL and colleagues (2023) suggests no deleterious impact of low dose inhibition of MTORC1 in biohackers through the COVID-19 pandemic, which I find encouraging since this was an older population (61+/- 10 years).
You know, I hadn't thought about it before, but I'm sure canine life extension will be only slightly less profitable than human life expansion (in the near term).
Not sure there is any real news here.
Yes, better control of glucose metabolism is well know to improve lifespan and health. But this effect will depend to an unknown extent on genotype/genetic background and of course, diet, age, and sex.
Ditto for rapamycin. The mouse studies on rapamycin and longevity increases are impressive bit this is now old news. Rapamycin is effect in both sexes of mice and can extend life expectancies even after the mouse equivalent if middle age (20 months and up).
It would be good to know if and how this positive rapamycin effect interacts with exposure to pathogens as a function if sex and age and genotype.
Recent data from Kaeberlein TL and colleagues (2023) suggests no deleterious impact of low dose inhibition of MTORC1 in biohackers through the COVID-19 pandemic, which I find encouraging since this was an older population (61+/- 10 years).
https://pubmed.ncbi.nlm.nih.gov/37191826/
You know, I hadn't thought about it before, but I'm sure canine life extension will be only slightly less profitable than human life expansion (in the near term).